Brenda departed from her family's residence in Brookwood, Alabama on July 2, 1988. She was accompanied by an unidentified male at the time. Brenda told her mother she was going to visit friends who lived in Abernant, Alabama, approximately ten miles northeast of her family's home.

Brenda was last seen at a residence across the street from Hosmer's Grocery on Highway 216 in Abernant later during the day. She was dropped off by one of her friends at the house to visit other friends, but her friends weren't home and Brenda's driver left her standing on the doorstep. She has never been heard from again. Authorities believe she disappeared under suspicious circumstances. Her case remains unsolved.